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Citations

Hintz RJ, Johnson KC. The effect of particle size distribution on dissolution rate and oral absorption. Int J Pharm. 51 (1989) 9-17.

Sheng JJ, Sirois PJ, Dressman JB, Amidon GL. Particle Diffusional Layer Thickness in a USP Dissolution Apparatus II: A Combined Function of Particle Size and Paddle Speed. J Pharm Sci. Published online ahead of print.

Okazaki A, Mano T, Sugano K. Theoretical Dissolution Model of Poly-Disperse Drug Particles in Biorelevant Media. J Pharm Sci. 97 (2008) 1843-1852.

Gao L, Zhang D, Chen M, Duan C, Dai W, Jia L, Zhao W. Studies on pharmacokinetics and tissue distribution of oridonin nanosuspensions. Int J Pharm. Article in Press.

Simon LL, Introvigne M, Fischer U, Hungerbűhler. Batch reactor optimization under liquid swelling safety constraint. Chemical Engineering Science. 63 (2008) 770-781.

Sugano K, Okazaki A, Sugimoto S, Tavornvipas S, Omura A, Mano T. Solubility and dissolution profile assessment in drug discovery. Drug Metab Pharmacokinet. 22 (2007) 225-254.

Takano R, Sugano K, Higashida A, Hayashi Y, Machida M, Aso Y, Yamashita S. Oral Absorption of Poorly Water-Soluble Drugs: Computer Simulation of Fraction Absorbed in Humans from a Miniscale Dissolution Test. Pharm Res. 23 (2006) 1144-56.

Simon LL, Fischer U, Hungerbuhler K. Modeling of a three-phase industrial batch reactor using a hybrid first-principles neural-network model. Ind Eng Chem Res. 45 (2006) 7336-7343.

Cabri W, Ghetti P, Alpegiani M, Pozzi G, Justo-Erbez A, Perez-Martinez JI, Villalon-Rubio R, Monedero-PeralesMC, Munoz-Ruiz A. Cefdinir: a comparative study of anhydrous vs. monohydrate form - microstructure and tabletting behaviour. European Journal of Pharmaceutics and Biopharmaceutics. 64 (2006) 212-221.

Galli C. Experimental determination of the diffusion boundary layer width of micron and submicron particles. Int J Pharm. 313 (2006) 114-122.

Jinno J, Kamada N, Miyake M, Yamada K, Mukai T, Odomi M, Toguchi H, Liversidge GG, Higaki K, Kimura T. Effect of particle size reduction on dissolution and oral absorption of a poorly water-soluble drug, cilostazol, in beagle dogs. J Control Release. 111 (2006) 56-64.

Mansbach RS, Moore RA. Formulation considerations for the development of medications with abuse potential. Drug and Alcohol Dependence. 83 (supplement 1) (2006) S15-S22.

Hecq J. Deleers M, Fanara D, Vranckx H, Amighi K. Preparation and characterization of nanocrystals for solubility and dissolution rate enhancement of nifedipine. Int J Pharm. 299 (2005) 167-77.

Tinke AP, Vanhoutte K, De Maesschalck R, Verheyen S, De Winter H. A new approach in the prediction of the dissolution behavior of suspended particles by means of their particle size distribution. J Pharm Biomed Anal. 39 (2005) 900-7.

Sertsou G. Analytical derivation of time required for dissolution of monodisperse drug particles. J Pharm Sci. 93 (2004) 1941-4.

Bosch HW, Skapin SD, Matijevic E. Preparation and characterization of finely dispersed drugs. 5. Ethyl 3,5-di(acetylamino)-2,4,6-triiodobenzoate. Colloids and Surfaces A: Physicochem. Eng. Aspects. 250 (2004) 43-50.

Balbach S, Korn C. Pharmceutical evaluation of early development candidates "the 100 mg-approach". Int J Pharm. 275 (2004) 1-12.

Lansky P, Lanska V, Weiss M. A stochastic differential equation model for drug dissolution and its parameters. Journal of Controlled Release. 100 (2004) 267-274.

Fiese EF. General pharmaceutics - The new physical pharmacy. J Pharm Sci. 92 (2003) 1331-1342.

Laitinen N. Opening new perspectives for visual characterisation of pharmaceutical solids. Doctoral dissertation 2003.  University of Helsinki, Faculty of Science, Department of Pharmacy.

Shan GU, Igarashi K, Ooshima H. Dissolution kinetics of crystals in suspension and its application to L-aspartic acid crystals. Chem Eng J. 288 (2002) 53-8.

Chambin O, Berard V, Rochat-Gonthier MH, Pourcelot Y. Dry absorbed emulsion: 2. Dissolution behaviour of an intricate formulation. Int J Pharm. 235 (2002) 169-178.

Lee MS, Huang CL, Huang SH, Chen YP, Chen CJ, Wen KC. A comparative study on the dissolution profiles of commercial hydrochlorothiazide tablets. Journal of Food and Drug Analysis 10 (2002) 18-24.

Friend DR, Parry GE, Francis T, Kupperblatt G, Chrai SS, Slack G.  Mathematical modeling of a novel controlled-release dosage form.  Drug Delivery Technology 1 (2001) 36-43.

Yu LX. An integrated model for determining causes of poor oral drug absorption.  Pharm Res 16 (1999) 1883-7.

Lee MS, Chang YC, Shih CC, et al. Study on dissolution profile of commercial glyburide tablets.  J  Food Drug Anal. 7 (1999) 83-93.

Carstensen JT, Dali M. Particle size distributions in mesh cuts and microscopically estimated volumetric shape factors. Drug Dev Ind Pharm. 25 (1999) 347-52.

Kalampokis A, Argyrakis P, Macheras P. Heterogeneous tube model for the study of small intestinal flow. Pharm Res. 16 (1999) 87-91.

Dali MV, Carstensen JT. Particle size distributions from multiparticulate dissolution. Drug Dev Ind Pharm. 24 (1998) 637-44.

Curatolo W. Physical chemical properties of oral drug candidates in the discovery and exploratory development settings. PSTT. 1 (1998) 387-93.

Pereira De Almeida L, Simões S, Brito P, Portugal A, Figueiredo M.  Modeling dissolution of sparingly soluble multisized powders. J Pharm Sci. 86 (1997) 726-32.

Chakrabarti S,  Southard MZ. Control of poorly soluble drug dissolution in conditions simulating the gastrointestinal tract flow. 2.  Cocompression of drugs with buffers. J Pharm Sci. 86 (1997) 465-69.

Simões S, Pereira de Almeida L, Figueiredo M. Testing the applicability of classical diffusional models to polydisperse systems. Int J Pharm. 139, (1996) 169-76.

Tromelin A, Habillon S, Andrés C, Pourcelot Y, Chaillot B. Relationship between particle size and dissolution rate of bulk powders and sieving characterized fractions of two qualities of orthoboric acid. Drug Dev Ind Pharm. 22 (9&10) (1996) 977-86.

de Villiers MM. Influence of agglomeration of cohesive particles on the dissolution behaviour of furosemide powder. Int J Pharm. 136 (1996) 175-9.

Yu LX, Crison JR, Amidon GL. Compartmental transit and dispersion model analysis of small intestinal transit flow in humans. Int J Pharm. 140 (1996) 111-8.

Yu LX, E Lipka, Crison JR, Amidon GL. Transport approaches to the biopharmaceutical design of oral drug delivery systems: prediction of intestinal absorption. Adv Drug Del Rev. 19 (1996) 359-76.

Amidon GL, Lennernäs H, Shah VP, Crison JR. A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability. Pharm Res. 12 (1995) 413-20.

Ueda S, Yamaguchi H, Kotani M, Kimura S, Tokunaga Y, Kagayama A, Hata T. Development of a novel drug release system, time-controlled explosion system (TES). II. Design of multiparticulate TES and in vitro drug release properties. Chem Pharm Bull. 42 (2) (1994) 359-63.

Birat M, Anderberg EK, Barnett MI, Nyström C. Physicochemical aspects of drug release. XV. Investigation of diffusional transport in dissolution of suspended, sparingly soluble drugs. Int J Pharm. 80 (1992) 191-201.

Farin D, Avnir D. Use of fractal geometry to determine effects of surface morphology on drug dissolution.  J Pharm Sci. 81 (1992) 54-7.

Book citations

Johansson F, Paterson R. Chapter 21 - Physiologically Based in Silico Models for the Prediction of Oral Drug Absorption. Drug Absorption Studies. ed. Ehrhardt C, Kim KJ. 2008 Springer ISBN 9780387749006.

Johnson KC. Chapter 1 - Dissolution: Fundamentals of In Vitro Release and the Biopharmaceutics Classification System. Pharmaceutical Product Development In Vitro-In Vivo Correlation. ed. Chilukuri DM, Sunkara G, Young D. 2007 Informa Health Care. ISBN 0849338271.

Ungell AL, Abrahamsson B. Chapter 4 - Biopharmaceutical Support in Candidate Drug Selection. Pharmaceutical Preformulation and Formulation:  A Practical Guide from Candidate Drug Selection to Commercial Dosage Form. Gibson M editor. 2004 Informa Health Care. ISBN 1574911201.

Granero GE, Ramachandran C, Amidon GL. Chapter 8 - Gastrointestinal Dissolution and Absorption of Drugs. Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability. ed. van de Waterbeemd H, Lennernas H, Artursson P. 2003 Wiley-VCH. ISBN 352730438X.

Yu LX, Ellison CD, Hussain AS. Predicting Human Oral Bioavailability using In Silico Models.  Applications of Pharmacokinetic Principles in Drug Development. ed. Krishna R. 2003 Springer. ISBN 0306477661.

Carstensen JT. Advanced Pharmaceutical Solids. 2001 CRC Press. ISBN 0824704312.

Dressman JB. Oral Drug Absorption: Prediction and Assessment. 2000 Informa Health Care. ISBN 0824702727.

Crison JR. Chapter 5 - Biopharmaceutical Aspects of Water-Insoluble Drugs for Oral Drug Delivery. Water-Insoluble Drug Formulation. ed. Liu R. 2000 CRC Press. ISBN 1574911058.

McNamara DP, Vieira ML, Crison JR. Chapter 5 - Dissolution of Pharmaceuticals in Simple and Complex Systems. Transport Processes in Pharmaceutical Systems. ed. Amidon GL, Lee PI, Topp EM. 2000 CRC Press. ISBN 0824766105.

Yu LX, Gatlin L, Amidon GL. Chapter 10 - Predicting Oral Drug Absorption. Transport Processes in Pharmaceutical Systems. ed. Amidon GL, Lee PI, Topp EM. 2000 CRC Press. ISBN 0824766105.

Inskeep PB, Darrington RT. Chapter 1 - Utilization of biopharmaceutical and pharmacokinetic principles in the development of veterinary controlled release drug delivery systems. Controlled Release Veterinary Drug Delivery: Biological and Pharmaceutical Considerations. ed. Rathbone MJ, Gurny R. 2000 Elsevier Science.

Sinko CM. Chapter 14 - Granulation Characterization: Methods and Significance. Handbook of Pharmaceutical Granulation Technology. ed. Parikh DM. 1997 Marcel Dekker. ISBN 0824798821.

Randall CS. Chapter 6 - Particle Size Distribution. Physical Characterization of Pharmaceutical Solids. Brittain HG. 1995 Informa Health Care. ISBN 0824793722.

Wagner JG. Pharmacokinetics for the Pharmaceutical Scientist. 1993 CRC Press. ISBN 1566760321.

Banakar U. Pharmaceutical Dissolution Testing. 1991 Informa Healthcare. ISBN 0824785673.

Lu ATK, Frisella ME, Johnson KC. Dissolution modeling: factors affecting the dissolution rates of polydisperse powders. Pharm Res. 10 (1993) 1308-14.

Sheng JJ, Sirois PJ, Dressman JB, Amidon GL. Particle Diffusional Layer Thickness in a USP Dissolution Apparatus II: A Combined Function of Particle Size and Paddle Speed. J Pharm Sci. Published online ahead of print.

Sugano K, Okazaki A, Sugimoto S, Tavornvipas S, Omura A, Mano T. Solubility and dissolution profile assessment in drug discovery. Drug Metab Pharmacokinet. 22 (2007) 225-254.

Mangin D, Garcia E, Gerard S, Hoff C, Klein JP, Veesler S. Modeling of the dissolution of a pharmaceutical compound. J Cryst Growth 286 (2006) 121-125.

Jinno J, Kamada N, Miyake M, Yamada K, Mukai T, Odomi M, Toguchi H, Liversidge GG, Higaki K, Kimura T. Effect of particle size reduction on dissolution and oral absorption of a poorly water-soluble drug, cilostazol, in beagle dogs. J Control Release. 111 (2006) 56-64.

Hecq J. Deleers M, Fanara D, Vranckx H, Amighi K. Preparation and characterization of nanocrystals for solubility and dissolution rate enhancement of nifedipine. Int J Pharm. 299 (2005) 167-77.

Sertsou G. Analytical derivation of time required for dissolution of monodisperse drug particles. J Pharm Sci. 93 (2004) 1941-4.

Horkovics-Kovats S. Characterization of an active pharmaceutical ingredient by its dissolution properties: amoxicillin trihydrate as a model drug. Chemotherapy 50 (2004) 234-44.

Fiese EF. General pharmaceutics - The new physical pharmacy. J Pharm Sci. 92 (2003) 1331-1342.

Shan GU, Igarashi K, Ooshima H. Dissolution kinetics of crystals in suspension and its application to L-aspartic acid crystals. Chem Eng J. 288 (2002) 53-8. 

Wang JZ, Flanagan DR. General solution for diffusion-controlled dissolution of spherical particles. 1. Theory. J Pharm Sci. 88 (1999) 731-8.

Curatolo W. Physical chemical properties of oral drug candidates in the discovery and exploratory development settings. PSTT. 1 (1998) 387-93.

Okimoto K, Miyake M, Ibuki R, et al. Dissolution mechanism and rate of solid dispersion particles of nilvadipine with hydroxypropylmethylcellulose. Int J Pharm. 159 (1997) 85-93.

Pereira De Almeida L, Simões S, Brito P, Portugal A, Figueiredo M. Modeling dissolution of sparingly soluble multisized powders. J Pharm Sci. 86 (1997) 726-32.

Simões S, Pereira de Almeida L, Figueiredo M. Testing the applicability of classical diffusional models to polydisperse systems. Int J Pharm. 139, (1996) 169-76.

de Villiers MM. Influence of agglomeration of cohesive particles on the dissolution behaviour of furosemide powder. Int J Pharm. 136 (1996) 175-9.

Dali MV, Carstensen JT. Effect of change in shape factor of a single crystal on its dissolution behavior. Pharm Res. 13 (1996) 155-62.

Book citations

Johnson KC. Chapter 1 - Dissolution: Fundamentals of In Vitro Release and the Biopharmaceutics Classification System. Pharmaceutical Product Development In Vitro-In Vivo Correlation. ed. Chilukuri DM, Sunkara G, Young D. 2007 Informa Health Care. ISBN 0849338271.

Water-Insoluble Drug Formulation. ed. Liu R. 2000 CRC Press. ISBN 1574911058.

Dressman JB. Oral Drug Absorption: Prediction and Assessment. 2000 Informa Health Care. ISBN 0824702727.

Yu LX, Gatlin L, Amidon GL. Chapter 10 - Predicting Oral Drug Absorption. Transport Processes in Pharmaceutical Systems. ed. Amidon GL, Lee PI, Topp EM. 2000 CRC Press. ISBN 0824766105.

Inskeep PB, Darrington RT. Chapter 1 - Utilization of biopharmaceutical and pharmacokinetic principles in the development of veterinary controlled release drug delivery systems. Controlled Release Veterinary Drug Delivery: Biological and Pharmaceutical Considerations. ed. Rathbone MJ, Gurny R. 2000 Elsevier Science.

Macheras P, Reppas C, Dressman JB. Biopharmaceutics of Orally Administered Drugs. 1995 Ellis Horwood Limited. ISBN 0131080938.

Wagner JG. Pharmacokinetics for the Pharmaceutical Scientist. 1993 CRC Press. ISBN 1566760321.

Johnson KC, Swindell AC. Guidance in the setting of drug particle size specifications to minimize variability in absorption. Pharm Res. 13 (1996) 1795-8.

Okazaki A, Mano T, Sugano K. Theoretical Dissolution Model of Poly-Disperse Drug Particles in Biorelevant Media. J Pharm Sci. 97 (2008) 1843-1852.

Avdeef A, Kansy M, Bendels S, Tsinman K. Absorption-excipient-pH classification gradient maps: Sparingly soluble drugs and the pH partition hypothesis. Eur J Pharm Sci. 33 (2008) 29-41.

Yamashita T, Dohta Y, Nakamura T, Fukami T. High-speed solubility screening assay using ultra-performance liquid chromatography/mass spectrometry in drug discovery. Journal of Chromatography A. 1182 (2008) 72-76.

Alsenz J, Kansy M. High throughput solubility measurement in drug discovery and development. Advanced Drug Delivery Reviews. 59 (2007) 546-567.

Sugano K, Okazaki A, Sugimoto S, Tavornvipas S, Omura A, Mano T. Solubility and dissolution profile assessment in drug discovery. Drug Metab Pharmacokinet. 22 (2007) 225-254.

Fagerholm U. Prediction of human pharmacokinetics - gastrointestinal absorption. Journal of Pharmacy and Pharmacology. 59 (2007) 905-916.

Maas J, Kamm W, Hauck G. An integrated early formulation strategy - from hit evaluation to preclinical candidate profiling. European Journal of Pharmaceutics and Biopharmaceutics. 66 (2007) 1-10.

Stegemann S, Leveiller F, Franchi D, de Jong H, Linden H. When poor solubility becomes an issue: from early stage to proof of concept. European Journal of Pharmaceutical Sciences. 31 (2007) 249-261.

Remenar JF. Improving oral bioavailability through inhibition of crystallization after dosing. American Pharmaceutical Review. 10(2) (2007) 84-9.

        Grabowski T. Farmakokinetyka i Biofarmacja. www.biokinetica.pl/farmakokinetyka.pdf

Yalkowsky SH, Johnson JLH, Sanghvi T, Machatha SG. A ‘Rule of Unity’ for Human Intestinal Absorption. Pharm Res. 23 (2006) 2475-81.

Thomas VH, Bhattachar S, Hitchingham L, Zocharski P, Naath M, Surendran N, Stoner CL, El-Kattan A. The road map to oral bioavailability: an industrial perspective. Expert Opin Drug Metab Toxicol. 2 (2006) 591-606.

Renslo AR, Luehr GW, Gordeev MF. Recent developments in the identification of novel oxazolidinone antibacterial agents. Bioorg Med Chem. 14 (2006) 4227-40.

United States Patent 7026508 (2006).

Valko K, Reynolds DP. High-throughput physicochemical and in vitro ADMET screening.  Am J Drug Deliv. 3 (2005) 83-100.

Li S, He H, Parthiban LJ, Yin H, Serajuddin ATM. IV-IVC considerations in the development of immediate-release oral dosage form. J Pharm Sci. 94 (2005) 1396-1417.

Tinke AP, Vanhoutte K, Vanhoutte F, De Smet M, De Winter H. Laser diffraction and image analysis as a supportive analytical tool in the pharmaceutical development of immediate release direct compression formulations. Int J Pharm. 297 (2005) 80-8.

Avdeef A. The rixe of PAMPA. Expert Opin Drug Metab Toxicol. 1 (2005) 325-342.

Avdeef A. Modelling drug absorption with the MAD model, based on permeability and solubility. Clin Exp Pharm Phys. (Suppl) (2004) A29.

Neervannan S. Stategies to impact solubility and dissolution rate during drug lead optimization: salt selection and prodrug design approaches. American Pharmaceutical Review. 7 (2004) 108-13.

Poggesi I. Predicting human pharmacokinetics from preclinical data. Curr Opin Drug Discov Devel. 7 (2004) 100-111.

Rasenack N, Muller BW. Micron-size drug particles: common and novel micronization techniques. Pharm Dev Technol. 9 (2004) 1-13.

Huang LF, Tong WQ. Impact of solid state properties on developability assessment of drug candidates. Adv Drug Deliv Rev, 56 (2004) 321-34.

Singhal D, Curatolo W. Drug polymorphism and dosage form design: a practical perspective. Adv Drug Deliv Rev. 56 (2004) 335-347.

Faassen WA. Biopharmaceutical aspects of oral drug delivery. Doctoral thesis. Utrecht University. 2004.

Martini LG, Crowley PJ. Physicochemical approaches to enhancing oral absorption. Pharmaceutical Technology Europe. Sep 1 2004.

United States Patent 20040044241 (2004).

Tolle-Sander S, Grill A, Joshi H, Kapil R, Persiani S, Polli JE. Characterization of dexloxiglumide in vitro biopharmaceutical properties and active transport. J Pharm Sci. 92 (2003) 1968-80.

Sanghvi T, Ni N, Mayersohn M, Yalkowsky SH. Predicting Passive Intestinal Absorption Using A Single Parameter. QSAR & Combinatorial Science. 22 (2003) 247-257.

Hilgers AR, Smith DP, Biermacher JJ, Day JS, Jensen JL, Sims SM, Adams WJ, Friis JM, Palandra J, Hosley JD, Shobe EM, Burton PS. Predicting Oral Absorption of Drugs: A Case Study with a Novel Class of Antimicrobial Agents. Pharm Res. 20 (2003) 1149-1155.

Fiese EF. General pharmaceutics - The new physical pharmacy. J Pharm Sci. 92 (2003) 1331-1342.

Gombar VK, Silver IS, Zhao Z. Role of ADME Characteristics in Drug Discovery and Their In Silico Evaluation: In Silico Screening of Chemicals for their Metabolic Stability. Curr Top Med Chem. 3 (2003) 1205-1225.

Bergstrom CAS, Strafford M, Lazorova L, Avdeef A, Luthman K, Artursson P. Absorption Classification of Oral Drugs Based on Molecular Surface Properties. J Med Chem. 46 (2003) 558-570.

Laitinen N. Opening new perspectives for visual characterisation of pharmaceutical solids. Doctoral dissertation 2003.  University of Helsinki, Faculty of Science, Department of Pharmacy.

Burton PS, Goodwin JT, Vidmar TJ, Amore BM. Predicting Drug Absorption: How Nature Made It a Difficult Problem. J Pharmacol Exp Ther. 303 (2002) 889-895.

Stenberg P, Bergstrom CAS, Luthman K, Artursson P. Theoretical predictions of drug absorption in drug discovery and development. Clin Pharmcokinet. 41 (2002) 877-899.

Egan WJ, Lauri G. Prediction of intestinal permeability. Adv Drug Deliver Rev. 54 (2002) 273-289.

Andersen K, Buur A. Moderne Laegemiddelforskning. Dansk Kemi. 82 (2001) 40-4.

Stenberg P. Computational models for the prediction of intestinal membrane permeability. Dissertation. Uppsala University. 2001.

Ohm A. Interaction of bay t 3839 coprecipitates with insoluble excipients. Eur J Pharm Biopharm. 49 (2000) 183-9.

Stewart BH, Wang Y, Surendran N. Ex vivo approaches to predicting oral pharmacokinetics in humans. Annu Rep Med Chem. 35 (2000) 299-307.

Blake JF.  Chemoinformatics – predicting the physicochemical properties of “drug-like” molecules. Curr Opin Biotech. 11 (2000) 104-7.

Boxenbaum H. Absorption potential and its variants. Pharm Res. 16 (1999) 1893.

Curatolo W. Physical chemical properties of oral drug candidates in the discovery and exploratory development settings. PSTT. 1 (1998) 387-93.

De Vrueh RLA, Smith PL, Lee CP. Transport of L-valine-acyclovir via the oligopeptide transporter in the human intestinal cell line. J Pharmacol Exp Ther. 286 (1998) 1166-70.

Book citations

Johansson F, Paterson R. Chapter 21 - Physiologically Based in Silico Models for the Prediction of Oral Drug Absorption. Drug Absorption Studies. ed. Ehrhardt C, Kim KJ. 2008 Springer ISBN 9780387749006.

van de Waterbeemd H. Chapter 2 - Physicochemical Properties in Drug Profiling. Molecular Drug Properties: Measurement and Prediction. Mannhold R. 2007 Wiley-VCH. ISBN 3527317554.

Tong WQ. Chapter 5 - Practical aspects of solubility determination in pharmaceutical preformulation. Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics.  ed. Augustinjns P, Brewster ME. 2007 American Association of Pharmaceutical Scientists. ISBN 9780387691497.

Brewster ME, Mackie C, Noppe M, Lampo A, Loftsson T. Chapter 8 - The use of solubilizing excipients and approaches to generate toxicology vehicles for contemporary drug pipelines. Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics.  ed. Augustinjns P, Brewster ME. 2007 American Association of Pharmaceutical Scientists. ISBN 9780387691497.

Li S, Mueller-Zsigmondy M, Yin H. Chapter 4 - The Role of In Vitro-In Vivo Correlation in Product Development and Life Cycle Management. Pharmaceutical Product Development In Vitro-In Vivo Correlation. ed. Chilukuri DM, Sunkara G, Young D. 2007 Informa Health Care. ISBN 0849338271.

Johnson KC. Chapter 1 - Dissolution: Fundamentals of In Vitro Release and the Biopharmaceutics Classification System. Pharmaceutical Product Development In Vitro-In Vivo Correlation. ed. Chilukuri DM, Sunkara G, Young D. 2007 Informa Health Care. ISBN 0849338271.

Petricoul O, Cosson V, Fuseau E, Marchand M. Population models for drug absorption and enterohepatic recycling. Pharmacometrics The Science of Quantitative Pharmacology. Ette EI, Williams PJ editors. 2007 John Wiley & Sons, Inc. ISBN 9780471677833.

van de Waterbeemd H. Property-Based Lead Optimization. Pharmacokinetic Profiling in Drug Research: Biological, Physicochemical, and Computational Strategies. Testa B, Krämer SD, Wunderli-Allenspach H, Folkers G editors. 2006 Verlag Helvetica Chimica Acta/Wiley-VCH. ISBN 3906390357.

Avdeef A. High-Throughput Solubility, Permeability, and the MAD PAMPA Model. Pharmacokinetic Profiling in Drug Research: Biological, Physicochemical, and Computational Strategies. Testa B, Krämer SD, Wunderli-Allenspach H, Folkers G editors. 2006 Verlag Helvetica Chimica Acta/Wiley-VCH. ISBN 3906390357.

Hageman MJ. Chapter 5 - Solubility, Solubilization and Dissolution in Drug Delivery During Lead Optimization. Optimizing the "Drug Like" Properties of Leads in Drug Discovery. ed. Borchardt RT, Kerns EH, Hageman MJ, Thakker DR, Stevens JL. 2006 Springer New York.  ISBN 9780387340562.

Rohrs BR. Chapter 7 - Biopharmaceutics Modeling and the Role of Dose and Formulation on Oral Exposure. Optimizing the "Drug Like" Properties of Leads in Drug Discovery. ed. Borchardt RT, Kerns EH, Hageman MJ, Thakker DR, Stevens JL. 2006 Springer New York.  ISBN 9780387340562.

Di L, Kerns EH. Chapter 8 - Application of Physicochemical Data to Support Lead Optimization by Discovery Teams. Optimizing the "Drug Like" Properties of Leads in Drug Discovery. ed. Borchardt RT, Kerns EH, Hageman MJ, Thakker DR, Stevens JL. 2006 Springer New York.  ISBN 9780387340562.

Burton PS, Poggesi I, Germani M, Goodwin JT. Chapter 9 - Computational Models Supporting Lead Optimization in Drug Discovery. Optimizing the "Drug Like" Properties of Leads in Drug Discovery. ed. Borchardt RT, Kerns EH, Hageman MJ, Thakker DR, Stevens JL. 2006 Springer New York.  ISBN 9780387340562.

Iliadis A, Macheras P. Modeling in Biopharmaceutics, Pharmacokinetics and Pharmacodynamics: Homogeneous and Heterogeneous Approaches. 2006 Springer. ISBN 0387281789.

Chapter 3 - Absorption. Pharmacokinetics and Metabolism in Drug Design. ed. Smith DA, van de Waterbeemd, Walker DK. 2006 Wiley-VCH. ISBN 3527313680.

Pudipeddi M, Serajuddin ATM, Mufson D. Chapter 3 - Integrated Drug Product Development-From Lead Candidate Selection to Life-Cycle Management.  The Process of New Drug Discovery and Development. Smith CG, O'Donnell JT ed. 2006 Informa Health Care. ISBN 0849327792.

Hilfiker R, Blatter F, von Raumer M. Relevance of solid-state properties for pharmaceutical products. Polymorphism: in the Pharmaceutical Industry. ed. Hilfiker R. 2006 Wiley-VCH.  ISBN 3527311467.

Quallich GJ, Chapter 12 - Selection of the Drug Form in Exploratory Development. Fundamentals of Early Clinical Drug Development: From Synthesis Design to Formulation. ed. Abdel-Magid AF, Caron S. 2006 John Wiley & Sons. ISBN-10 0471692786.

Sathe PM, Raw AS, Ouderkirk LA, Yu LX, Hussain AS. Chapter 8 - Drug product performance, In Vitro. Generic Drug Product Development: Solid Oral Dosage Forms. ed. Shargel L, Kanfer I. 2005 Informa Health Care. ISBN 0824754603.

Lombardo F, Absorption Prediction. Pharmaceutical Profiling in Drug Discovery For Lead Selection. ed. Borchardt RT, Kerns EH, Lipinski CA, Thakker DR, Wang B. 2004 Springer. ISBN 0971176795.

van de Waterbeemd H. Chapter 1 - Physico-chemical Approaches to Drug Absorption. Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability. ed. van de Waterbeemd H, Lennernas H, Artursson P. 2003 Wiley-VCH. ISBN 352730438X.

van de Waterbeemd H, Jones BC. Chapter 1 - Predicting Oral Absorption and Bioavailability. Progress in Medicinal Chemistry Volume 41. ed. King FD, Oxford AW. 2003 Elsevier Science. ISBN 0444511423.

Granero GE, Ramachandran C, Amidon GL. Chapter 8 - Gastrointestinal Dissolution and Absorption of Drugs. Drug Bioavailability: Estimation of Solubility, Permeability, Absorption and Bioavailability. ed. van de Waterbeemd H, Lennernas H, Artursson P. 2003 Wiley-VCH. ISBN 352730438X.

Crison JR. Chapter 5 - Biopharmaceutical Aspects of Water-Insoluble Drugs for Oral Drug Delivery. Water-Insoluble Drug Formulation. ed. Liu R. 2000 CRC Press. ISBN 1574911058.

McNamara DP, Vieira ML, Crison JR. Chapter 5 - Dissolution of Pharmaceuticals in Simple and Complex Systems. Transport Processes in Pharmaceutical Systems. ed. Amidon GL, Lee PI, Topp EM. 2000 CRC Press. ISBN 0824766105.

Yu LX, Gatlin L, Amidon GL. Chapter 10 - Predicting Oral Drug Absorption. Transport Processes in Pharmaceutical Systems. ed. Amidon GL, Lee PI, Topp EM. 2000 CRC Press. ISBN 0824766105.

Inskeep PB, Darrington RT. Chapter 1 - Utilization of biopharmaceutical and pharmacokinetic principles in the development of veterinary controlled release drug delivery systems. Controlled Release Veterinary Drug Delivery: Biological and Pharmaceutical Considerations. ed. Rathbone MJ, Gurny R. 2000 Elsevier Science.

Lombardo F, Winter SM, Tremaine L, Lowe JA III. The anxieties of drug discovery and development. Integration of Pharmaceutical Discovery and Development: casehistories. ed. Borchardt RT. 1998 Springer. ISBN 0306457431.

Zhang Y, Johnson KC. Effect of drug particle size on content uniformity of low-dose solid dosage forms Int J Pharm. 154 (1997) 179-183.

Simons SJR. Chapter 27 - Liquid Bridges in Granules. Granulation, Volume 11 (Handbook of Powder Technology). Salman AD, Hounslow M, Seville JPK editors. 2007 Elsevier. ISBN 0444518711.

A.P. Tinke, K. Vanhoutte, F. Vanhoutte, M. De Smet and H. De Winter Laser diffraction and image analysis as a supportive analytical tool in the pharmaceutical development of immediate release direct compression formulations. Int J Pharm. 297 (2005) 80-8.

Rossetti D, Simons SJR, Pagliai P, Ward R, Fitzpatrick S. Predicting the performance of granulation binders through micro-mechanistic observations. Particle & Particle Systems Characterization. 21 (2004) 284-292.

Simons SJR, Rossetti D, Pagliai P, Ward R, Fitzpatrick S. Predicting the performance of granulation binders through micro-mechanistic observations. Powder Technol. 140 (2004) 280-9.

Lee CC, Chan LW, Heng PW. Use of a fluidized bed hammer mill for size reduction and classification: effects of process variables and starting materials on the particle size distribution of milled lactose batches. Pharm Dev Technol. 8 (2003) 431-42.

Johnson KC. Dissolution and absorption modeling: model expansion to simulate the effects of precipitation, water absorption, longitudinally changing intestinal permeability, and controlled release on drug absorption. Drug Dev Ind Pharm. 29 (2003) 833-42.

Dickhoff BH, de Boer AH, Lambregts D, Frijlink HW. The effect of carrier surface and bulk properties on drug particle detachment from crystalline lactose carrier particles during inhalation, as function of carrier payload and mixing time. Eur J Pharm Biopharm. 56 (2003) 291-302.

Mullarney MP, Hancock BC, Carlson GT, Ladipo DD, Langdon BA. The powder flow and compact mechanical properties of sucrose and three high-intensity sweeteners used in chewable tablets. Int J Pharm. 257 (2003) 227-36.

Kornchankul W, Hamed E, Parikh NH, Sakr A. Effect of drug proportion and mixing time on the content uniformity of a low dose drug in a high shear mixer. Pharmazie 57 (2002) 49-53.

Kato Y, Moroshima K, Hashizume M, et al. Further observation of content uniformity of D-alpha-tocopheryl acetate as an oily drug in granules obtained by wet granulation with a high-shear mixer. Drug Dev Ind Pharm. 27 (2001) 781-7.

Prescott JK, Garcia TP. A solid dosage and blend content uniformity troubleshooting diagram. Pharm Technol. 25 (2001) 68-88.

Kornchankul W, Parikh NH, Sakr A. Effect of process variables on the content uniformity of a low dose drug in a high shear mixer. Pharm Ind. 62 (2000) 305-11.

Book citations

Gibson M. Pharmaceutical Preformulation and Formulation:  A Practical Guide from Candidate Drug Selection to Commercial Dosage Form. 2004 Informa Health Care. ISBN 1574911201.

Stricker H. Arzneiformen-Entwicklung. 2003 Springer. ISBN 3540000682.

Carstensen JT. Advanced Pharmaceutical Solids. 2001 CRC Press. ISBN 0824704312.

Johnson KC. Dissolution and absorption modeling: model expansion to simulate the effects of precipitation, water absorption, longitudinally changing intestinal permeability, and controlled release on drug absorption. Drug Dev Ind Pharm. 29 (2003) 833-42.

Pole DL. Physical and biological Considerations for the Use of Nonaqueous Solvents in Oral Bioavailability Enhancement. J Pharm Sci. 97 (2008) 1071-1088.

Sugano K, Okazaki A, Sugimoto S, Tavornvipas S, Omura A, Mano T. Solubility and dissolution profile assessment in drug discovery. Drug Metab Pharmacokinet. 22 (2007) 225-254.

Kallen A. A simple absorption model for dose-escalating studies. Journal of Pharmacokinetics and Pharmacodynamics. 34 (2007) 251-261.

Stegemann S, Leveiller F, Franchi D, de Jong H, Linden H. When poor solubility becomes an issue: from early stage to proof of concept. European Journal of Pharmaceutical Sciences. 31 (2007) 249-261.

Jinno J, Kamada N, Miyake M, Yamada K, Mukai T, Odomi M, Toguchi H, Liversidge GG, Higaki K, Kimura T. Effect of particle size reduction on dissolution and oral absorption of a poorly water-soluble drug, cilostazol, in beagle dogs. J Control Release. 111 (2006) 56-64.

Thombre AG. Assessment of the feasibility of oral controlled release in an exploratory development setting. Drug Discov Today. 10 (2005) 1159-66.

Sertsou G. Analytical derivation of time required for dissolution of monodisperse drug particles. J Pharm Sci. 93 (2004) 1941-4.

Book citations

Brewster ME, Mackie C, Noppe M, Lampo A, Loftsson T. Chapter 8 - The use of solubilizing excipients and approaches to generate toxicology vehicles for contemporary drug pipelines. Solvent Systems and Their Selection in Pharmaceutics and Biopharmaceutics.  ed. Augustinjns P, Brewster ME. 2007 American Association of Pharmaceutical Scientists. ISBN 9780387691497.

Johnson KC. Chapter 1 - Dissolution: Fundamentals of In Vitro Release and the Biopharmaceutics Classification System. Pharmaceutical Product Development In Vitro-In Vivo Correlation. ed. Chilukuri DM, Sunkara G, Young D. 2007 Informa Health Care. ISBN 0849338271.

 


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